Musculoskeletal Disorders Axis

Leaders:
Richard Kremer
Henri Menard

Research Themes:
– Effects of Hormones and Tumors on the Skeleton
– Genetics and Development of the Skeleton
– Musculoskeletal Damage and Repair

The overall goals of the Musculoskeletal Disorders Axis are to improve our understanding of disease mechanisms and expedite the development of strategies for the prevention, diagnosis and management of musculoskeletal disorders.

Clinical investigators in this axis focus on the study of musculoskeletal disorders, particularly musculoskeletal repair and the biological and genetic basis of bone disorders and bone cancer. Current research projects include identification of molecular pathways of medical conditions affecting bones and joints, such as degenerative and inflammatory joint and disk diseases, primary and metastatic cancer, osteoporosis and axial/peripheral insufficiency fractures, and musculoskeletal development problems like osteogenesis imperfecta, congenital malformations and scoliosis.