Human Reproduction and Development Axis

Leaders:
Hugh Clarke
Paul Goodyer

Research Themes:
– Development of Germ Cells
– Development of the Fetus
– Adaption to Post-Natal Life

Research in the Human Reproduction and Development Axis is focused on the genetic and physiological basis of reproduction and infertility, and on the biology of development. Axis researchers focus on some of the major issues that affect society today, such as declining fertility rates, developmental disorders that arise during pregnancy, and the connection between environmental toxicants and reproductive failure.

A major focus of the clinical research of the axis is improving assisted reproduction. The Reproductive Centre has developed several novel methodologies in assisted reproductive technologies, including a new technique of oocyte cryopreservation, termed vitrification, which enabled women to preserve oocytes for future fertilization. Importantly, oocyte vitrification can also provide hope for patients with malignant diseases such as cancer, who need chemotherapy and therefore become infertile.